Oxford scientists have discovered a key underlying cause of a range of serious conditions including cancers and Motor Neurone Disease (MND). It’s important because if you know why something happens, you can try to do something about it and you are a lot closer to fixing it. So it was overwhelming when Professor Kristijan Ramadan and his team at Oxford’s Department of Oncology discovered that a naturally-occurring, but faulty, ‘protein plough’ is linked to a range of very serious conditions.Professor Ramadan explains that, if the body is working properly, proteins swoop in to repair lesions or damage to the DNA. Lesions can occur because of drinking, smoking, during illness or because of medicines.Professor Ramadan’s work gives hope that it will be possible to identify patients for whom the usual treatment is not going to work – enabling them to be given an alternative without waiting. ‘They occur all the time – and can be caused just through breathing Oxygen,’ says…



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