Scientists create supersensitive nanomaterials for DNA diagnostics and targeted drug delivery

Supersensitive nanomaterial. Credit: Vladimir Cherkasov et al./ACS Nano

In 1900, German physician Paul Ehrlich came up with the notion of a “magic bullet.” The basic idea is to inject a patient with smart particles capable of finding, recognizing, and treating a disease. Medicine has pursued the magic bullet ever since.

Russian researchers from the Moscow Institute of Physics and Technology and Prokhorov General Physics Institute, RAS, have made headway toward that goal. Led by MIPT’s Maxim Nikitin, the team published a paper in ACS Nano, presenting a smart material with unique properties, which holds promise for express DNA analysis and next-generation drugs against cancer and other serious diseases.
Delivering medications to the cells affected by a disease is a major bottleneck in diagnostics and therapy. The drugs should ideally reach the pathogenic cells only, without…

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